We offer molecular breeding services based on directed evolution techniques such as error-prone PCR and DNA shuffling. By constructing mutant libraries combined with high-throughput screening, we obtain target proteins or strains with improved performance (such as higher activity, greater stability, or altered substrate specificity).
When you need to quickly obtain a strain or protein mutant with better performance (higher activity, greater stability) without clear structural information, directed-evolution-style molecular breeding lets you bypass the high barrier of "rational design" — answering "when you don’t know exactly what to change, how do you find a better version."
Random mutagenesis (error-prone PCR) or in vitro recombination (DNA shuffling) introduces diverse mutations at the target gene/genome level to build a mutant library. Combined with targeted high-throughput screening or selective pressure, mutants with the desired trait improvement are enriched, achieving functional optimization without rational design.
Industrial enzyme molecular engineering, strain performance optimization, protein engineering research, etc.
Error-prone PCR, DNA shuffling, and other techniques available
Specific timeline confirmed at contract signing
Selected mutants delivered with a performance verification report
Improvement is possible without clear structural information
Submit your experimental plan and objectives
Technical advisor confirms the protocol and timeline
Pay a deposit of at least 50% of the project cost to enter production
Quality control documented throughout production
Settle the balance and complete acceptance
Standard, custom, and large orders all require a deposit of at least 50% of the contract value to begin. The timing for the remaining balance is agreed separately for each project.
Please complete acceptance within 1 month of receiving the product or report. Any concerns about the deliverable should be raised within this window; we will respond within 2 business days.