We design, construct, and viral-package chimeric antigen receptor (CAR) molecule vectors, covering single-chain antibody (scFv) selection, co-stimulatory domain combination optimization, and lentiviral/retroviral vector construction — providing molecular delivery tools for CAR-T, CAR-NK, and other cell therapy research.
When you need to design and deliver a chimeric antigen receptor molecule for CAR-T/CAR-NK cell therapy research, professional CAR vector construction helps you correctly assemble a complex multi-domain design and deliver it into immune cells — answering "how do you get immune cells to recognize and attack the target antigen."
A CAR molecule is typically constructed by linking an extracellular antigen-recognition domain (scFv), a hinge region, a transmembrane domain, and intracellular co-stimulatory signaling domains (such as CD28 or 4-1BB) in series with a CD3ζ signaling domain. After lentiviral or retroviral packaging, T cells/NK cells are infected to express the CAR molecule, enabling them to specifically recognize and kill target antigen-positive cells.
CAR-T/CAR-NK cell therapy research, tumor immunotherapy basic research, early-stage cell therapy product development, etc.
Co-stimulatory domains (CD28/4-1BB, etc.) can be combined as needed
Exact timeline assessed by vector design complexity
Vectors/virus delivered after sequencing verification
Covers both CAR-T and CAR-NK delivery scenarios
Submit your experimental plan and objectives
Technical advisor confirms the protocol and timeline
Pay a deposit of at least 50% of the project cost to enter production
Quality control documented throughout production
Settle the balance and complete acceptance
Standard, custom, and large orders all require a deposit of at least 50% of the contract value to begin. The timing for the remaining balance is agreed separately for each project.
Please complete acceptance within 1 month of receiving the product or report. Any concerns about the deliverable should be raised within this window; we will respond within 2 business days.